In response to the HHS’s Request for Information on artificial intelligence (AI) in clinical practice, organizations like ASCO, COA, and ACS CAN submitted feedback ahead of the February 23, 2026 deadline. HHS aims to expedite AI adoption through public insights on regulatory, reimbursement, and research considerations. ASCO emphasized the necessity of a unified federal regulatory framework to overcome barriers hindering AI integration in oncology practices. They advocated for data sharing and implementation of standards like mCODE and FHIR to enhance AI accuracy. COA expressed concerns about the financial and resource burdens of AI adoption in community settings, urging for incentives and simplified regulations. ACS CAN insisted on a solid regulatory framework for patient safety and privacy. All responses underscored AI’s potential to transform healthcare while maintaining that it should support, not replace, clinical expertise. These insights align with HHS’s overall AI strategy for health care innovation.
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