Thursday, July 31, 2025

Ambience Healthcare, Backed by OpenAI, Achieves $1 Billion Valuation

Ambience Healthcare, an AI startup based in San Francisco, has successfully secured $243 million in Series C funding, elevating its valuation over $1 billion. This funding round was spearheaded by Andreessen Horowitz and Oak HC/FT, with backing from previous investors like the OpenAI Startup Fund, Kleiner Perkins, and Optum Ventures, along with newcomers such as Frist Cressey Ventures and Smash Capital. The capital will enable Ambience to expand its presence in hospitals and clinics while increasing its team from 180 employees to enhance service delivery. Utilizing AI, Ambience alleviates administrative burdens for clinicians, thus addressing critical issues like physician burnout. Its technology integrates with major EHR systems, streamlining workflows and improving data accuracy. Ambience’s innovative solutions are already in practice at institutions like Cleveland Clinic and UCSF Health, signifying a robust trend toward AI-driven improvements in healthcare operations. OpenAI’s investment reflects strong confidence in Ambience’s potential to revolutionize clinical workflows.

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